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Mental Health · 6 min read

Anxiety & Mood Swings: What Is Going On

By the Mina team · Updated 7 November 2026

It is not "all in your head." The hormonal fluctuations of perimenopause can directly impact your brain chemistry, leading to increased anxiety, irritability, and sadness.

Why it happens

Oestrogen has a protective effect on the brain. As levels fluctuate and eventually drop, it affects neurotransmitters like serotonin (the "feel-good" hormone) and GABA (the calming neurotransmitter).

Strategies for Coping

  • Mindfulness Meditation: Even 10 minutes a day can lower cortisol levels. Apps like Calm or Headspace can be great starting points.
  • Regular Exercise: Physical activity releases endorphins, natural mood lifters. Yoga is particularly beneficial as it combines movement with breathwork.
  • Limit Stimulants: Caffeine and alcohol can exacerbate anxiety and disrupt sleep. Try cutting back to see if your mood stabilizes.
  • Talk Therapy: Cognitive Behavioral Therapy (CBT) has been shown to be effective for menopausal mood symptoms.

Self-Compassion

Be gentle with yourself. You are going through a significant biological change. Give yourself permission to rest and say "no" to unnecessary obligations.

Sources

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